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On September 11, 1945, Kolff performed the first successful hemodialysis session in history. The replacement of kidney function with artificial dialysis is one of the triumphs of modern medicine and technology, and has prolonged the lives of millions of individuals around the world.  Several challenges remain in renal replacement therapy for individuals with kidney failure. Much of the world’s population does not have access to renal replacement therapy due to economic and social inequalities. The technologies for renal replacment therapy have improved since the first successful use of hemodialysis, but our treatment options remain in principle very similar to Kolff’s apparatus. We conduct patient-oriented research in dialysis and continuous renal replacement therapies, ranging from epidemiology studies to physiologically-oriented studies to randomized controlled trials.

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